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Phenylalanine

DESCRIPTION/FUNCTION

L-Phenylalanine is classified as an essential amino acid. It can be converted to tyrosine, which in turn is converted to the excitatory catecholamine neurotransmitters (dopa, dopamine, norepinephrine, epinephrine). The 'L' form exists in food naturally. When it is made in a lab, both the 'L' and 'D' forms are produced. The 'L' form may be separated and sold by itself, or the mixture can be left together, which is sometimes called DLPA (DL-phenylalanine).

RDA (Recommended Dietary Allowance) for Adults

Phenylalanine plus tyrosine: 14 mg/kg/day.

MAJOR SOURCES

Animal proteins (dairy, eggs, fish, meat, poultry).

MAINTENANCE/THERAPEUTIC RANGE

L-Phenylalanine: 500 mg to 5,000 mg.
DL-Phenylalanine: 250 mg to 2,000 mg.

POSSIBLE THERAPEUTIC APPLICATIONS

Chronic fatigue syndrome, chronic pain (DLPA), depression (unipolar), Parkinson's disease.

COM MENTS

Since phenylalanine increases excitatory neurotransmitters, it should be taken early in the day to avoid sleep disturbances. Phenylalanine may help with weight loss by reducing appetite. DLPA can help with chronic pain if taken for at least two months. As with all amino acids, supplements should be taken on an empty stomach, or at least separate from protein foods.

CAUTIONS

If pregnant, avoid the 'D' and 'DL' forms. Do not combine with prescription medications for depression (especially MAOIs and neuroleptic drugs), Parkinson’s disease, or various psychoses, including schizophrenia. Avoid if you have PKU. Consult with your health practitioner if you have high blood pressure.

References
Jellin, JM, editor. Natural Medicines Comprehensive Database, 2007.
Pillepich, JA. The Nutraceutical Reference Guide, 2005
.

FOR PHENYLALANINE, CONSIDER THIS SUPPLEMENT:

Brain Energy
A.M. Brain Energy Cream

* * * * * *

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