Melatonin DESCRIPTION/FUNCTION Melatonin, produced by the pineal gland, is a naturally occurring hormone that is released into the bloodstream during periods of darkness. It plays a role in the body\'s circadian rhythm. Melatonin helps to regulate physiological functions that occur within a 24-hour period, including sleep patterns, and changes in body temperature, blood pressure, and heart rate. RDA (Recommended Dietary Allowance) for Adults None. MAJOR SOURCES Made in the body and nutritional supplements. MAINTENANCE/THERAPEUTIC RANGE 0.3 mg to 10 mg (higher doses, up to 50 mg, are used under medical supervision). POSSIBLE THERAPEUTIC APPLICATIONS Cancer (prostate: high doses and combined therapy), epilepsy, fibromyalgia, insomnia, jet lag, headache (cluster, migraine), tardive dyskinesia. COMMENTS Melatonin is produced in the body\'s pineal gland by converting tryptophan (an amino acid) to serotonin and then to melatonin. Melatonin should only be taken before bedtime, and at the same time every night. Exposure to full-spectrum light during the day helps the body\'s production of melatonin, and sleeping in total darkness is also important. Melatonin\'s sleep effects last about three to four hours. Quick release supplements help with falling asleep, and timed release supplements may benefit those who wake up several hours after falling asleep. Melatonin also has antioxidant properties. CAUTIONS Avoid if pregnant. Consult with your health practitioner if you have seizures, depression, or are taking immunosuppressants or CNS depressants. References Jellin, JM, editor. Natural Medicines Comprehensive Database, 2007. Pillepich, JA. The Nutraceutical Reference Guide, 2005. FOR MELATONIN, CONSIDER THESE SUPPLEMENTS: ● Melatonin, 1 mg, Two-Stage release ● Melatonin, 3 mg ● Sleep Formula ● Tryptophan The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professionals or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Your health is our major concern. * * * * * * Total Health Nutrients is a multi-faceted company, with operations in New York and New Jersey. We provide both services and products, such as: Nutritional Supplements: We carry the highest quality supplements to speed up your healing process. They were developed to contain the right proportions of vitamins, minerals, and essential fatty acids, without danger of toxic build-up and without dangerous side effects. Each ingredient is selected in consideration of its absorbability, competitive relationship with other nutrients, allergenic potential, and long-term safety. Also, our supplements are manufactured in a cGMP (current Good Manufacturing Practices) facility, ensuring you always get a pure product that meets label potency. Go to www.totalhealthnutrients.com to check out our selection of pure supplements. Personalized Vitamin Organizers: As an added service, we offer these compartmentalized containers filled with your supplement regimen, with each section labeled, for easy identification. For people who are rushed in the morning or who travel frequently, this service makes life a bit less complicated. Dietary Analysis: We use the most reliable computerized nutritional analysis program available. More than 29,000 foods, from all food groups, are accessed by our computer program, analyzing a person\'s usual dietary intake. The resulting reports provide the information in tabular and graphical formats. Metabolic Testing: This service measures how many calories you burn at various activities, and how many calories you need daily to lose/sustain/or increase your weight, depending on your goals. Having these numbers enables us to make your personalized plan as accurate as possible. TSFL Weight Loss Program: We proudly feature TSFL Weight Loss Program for patients that need to lose weight as quickly and safely as possible. Clinically proven by Johns Hopkins University - Take Shape For Life will help you reach your weight goal with Medifast Meals that are low calorie, low fat, and nutritionally balanced. There is no counting calories, carbs, or points. It is all done for you. Along the way, we will provide the care and support you need to succeed in maintaining your weight loss and health program for life. More info is available at www.rainbowdiet.tsfl.com.  1-888-THN-7284 www.totalhealthnutrients.com  Call Total Health Nutrients today, or visit our web site, for our great selection of high-quality nutritional supplements!

The majority of products for THN are manufactured by Douglas Laboratories. Throughout more than 50 years, Douglas Laboratories has offered unparalleled quality through the use of the finest raw materials, rigorous manufacturing practices, and several certifications and accreditations, including registration from NSF International cGMPs in accordance with USP31, ISO 9001 and IS0 17025 accreditation of in-house laboratories. Douglas Laboratories is committed to unprecedented quality through every step of manufacturing and quality control procedures.