Rheumatoid Arthritis (RA) Helpful Natural Supplements and Treatments OVERVIEW Rheumatoid arthritis (RA) is an autoimmune disease affecting the joints. The immune system attacks the synovial membranes lining the joints, causing inflammation and increased release of synovial fluid. The synovial membrane becomes thickened and the joint swells, damaging the joint and restricting movement. Joints affected include those of the arms (hands, wrists, elbows, shoulders) and the legs (ankles, feet, knees). Rheumatoid arthritis usually appears between the ages 20 and 40, and more women than men are affected. Initial symptoms are general and include fatigue and poor appetite. As the disease progresses, there is pain and swelling, joint redness and warmth, and morning stiffness. Symptoms are usually experienced on both sides of the body (bilateral). Another form of the disease affects children (juvenile rheumatoid arthritis). SUPPLEMENTS FOR RHEUMATOID ARTHRITIS There are several natural supplements that can help with RA. Consult with your healthcare provider to see which of the following supplements may be appropriate for you. Vitamins & Minerals Vitamin E – This fat-soluble antioxidant helps to protect the joints against oxidative damage caused by chronic inflammation. Less Helpful: vitamin B5, copper, selenium, zinc. Other Supplements Cetyl Myristoleate – CMO is an ester that is found in beavers, mice, and whales. It is usually manufactured from the myristoleic acid content of bovine (cattle) sources. It may act as a joint lubricant and as an anti-inflammatory agent. Omega-3 Fatty Acids – Fish oil contains omega-3 fatty acids that can reduce inflammation by acting on the prostaglandin, PGE3. Omega-6 Fatty Acids – The GLA (gamma-linolenic acid) that is found in some plant seeds (borage, black current, evening primrose) helps to reduce inflammation by acting on the prostaglandin, PGE1. Less Helpful: bromelain, SOD (superoxide dismutase). Herbs Cat's Claw – An herb found in the Peruvian Amazon, Cat's Claw (Uncaria tomentosa) contains unique alkaloids that have shown promise in reducing painful, swollen joints. Cayenne – When cayenne is applied topically (capsaicin cream), it can deplete substance P, which is a pain-mediating neurotransmitter. The result is that, when used over time, there is a reduction in pain. Ginger – This rhizome, which is related to turmeric, has both antioxidant and anti-inflammatory properties. Turmeric – This rhizome, a spice usually found in curry, also has antioxidant and anti-inflammatory properties. Less Helpful: boswellia. COMMENTS Conventional treatment includes medications to reduce inflammation and slow the progression of the disease. Other therapies include hot or cold packs, gentle exercise (especially in water), and yoga. Food allergies may contribute to RA, so keep a food diary to determine if any food is causing flare-ups. References Jellin, JM, editor. Natural Medicines Comprehensive Database, 2007. Pillepich, JA. The Nutraceutical Reference Guide, 2005. FOR RHEUMATOID ARTHRITIS, CONSIDER THESE SUPPLEMENTS: ● Age-Less Paks or Wellness Paks ● E-400 w/Selenium ● Omega-3 ● Omega-6 ● Curcumin (turmeric) ● Boswellin w/Curcumin The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professionals or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. 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