NAC (N-Acetyl-L-Cysteine):

A Special Amino Acid

DESCRIPTION/FUNCTION

NAC is a derivative of the amino acid, L-cysteine. It is more stable and better absorbed than cysteine. As a source of cysteine, NAC is used to increase levels of glutathione, an important tripeptide antioxidant (consists of the three amino acids, cysteine, glutamic acid, and glycine).

RDA (Recommended Dietary Allowance) for Adults

None.

MAJOR SOURCES

Pharmaceutical drugs (IV and inhalant) and nutritional supplements.

MAINTENANCE/THERAPEUTIC RANGE

500 mg to 2,000 mg.

POSSIBLE THERAPEUTIC APPLICATIONS

Bronchitis, cancer (colorectal), COPD (chronic obstructive pulmonary disease), epilepsy, flu, HIV/AIDS, immune function, liver support, memory loss

COMMENTS

NAC, as a precursor to glutathione, is used to protect the liver from various poisons, including mushroom (Amanita phalloides) and acetaminophen overdose. It is helpful for many lung and bronchial problems, often being used with an inhaler. Some health practitioners recommend increasing vitamin C intake to prevent cysteine from oxidizing to cystine.

CAUTIONS

Use with caution if you have a gastric ulcer. Take with food. Take NAC with sufficient water to reduce the chance of getting kidney stones.

References
Jellin, JM, editor. Natural Medicines Comprehensive Database, 2005.
Pillepich, JA. The Nutraceutical Reference Guide, 2005.

For A NAC SUPPLEMENT, TRY:

N-Acetyl-L-Cysteine (NAC)

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